What it is used for

Relapsing remitting multiple sclerosis in adults and children aged 10 and over

Read our guides:

Multiple sclerosis

Off-label uses

Doctors sometimes prescribe a medicine for a condition it is not officially licensed for. This is called off-label use. It is legal and common when there is good evidence it helps, and your doctor should explain why they are suggesting it.

Teriflunomide is not commonly used off-label.

How it works

Teriflunomide blocks an enzyme that fast-dividing immune cells need. This reduces the number of active immune cells that can attack the nerves, lowering the number of relapses.

Side effects

Like all medicines, Teriflunomide can cause side effects, although not everyone gets them. Many are mild and ease after the first few weeks.

Common side effects

diarrhoea
feeling sick
hair thinning
raised liver enzymes
headache
tingling

Tell your doctor or pharmacist if these bother you or do not go away.

Serious side effects

These are rare. Call 111 or contact your doctor straight away if you get:

yellowing of the skin or eyes, dark pee or pale poo
signs of infection, such as a high temperature or sore throat
a severe skin rash
a new cough or breathlessness

Call 999 if you have signs of a serious allergic reaction, such as swelling of your lips, mouth, throat or tongue, or trouble breathing.

You can report any side effect to the Yellow Card scheme, run by the medicines regulator.

Stopping and withdrawal

Important safety information

You need regular blood tests and blood pressure checks.
Avoid pregnancy. If you become pregnant, contact your team straight away for a washout treatment.

Questions about your medicine?

A pharmacist can answer questions about your medicines for free, without an appointment. You can also ask your GP for a medication review. Check if you can get free prescriptions.