What it is used for

Treating migraine attacks (some strengths available from pharmacies)
Treating cluster headache attacks (injection or nasal spray)

Read our guides:

Migraine

Off-label uses

Doctors sometimes prescribe a medicine for a condition it is not officially licensed for. This is called off-label use. It is legal and common when there is good evidence it helps, and your doctor should explain why they are suggesting it.

Sumatriptan is not commonly used off-label.

How it works

Sumatriptan acts on serotonin receptors around blood vessels and nerves in the head. It narrows widened blood vessels and blocks the release of chemicals that cause migraine pain.

Side effects

Like all medicines, Sumatriptan can cause side effects, although not everyone gets them. Many are mild and ease after the first few weeks.

Common side effects

feeling hot
tingling or heavy
tightness in the chest or throat
feeling sick
dizziness
feeling tired

Tell your doctor or pharmacist if these bother you or do not go away.

Serious side effects

These are rare. Call 111 or contact your doctor straight away if you get:

severe chest pain or tightness that does not go away. Call 999
signs of serotonin syndrome, such as confusion, high temperature and muscle twitching
fits

Call 999 if you have signs of a serious allergic reaction, such as swelling of your lips, mouth, throat or tongue, or trouble breathing.

You can report any side effect to the Yellow Card scheme, run by the medicines regulator.

Stopping and withdrawal

Important safety information

Not suitable if you have heart disease, peripheral arterial disease, uncontrolled high blood pressure or have had a stroke.
Do not take a second dose for the same attack if the first did not help.

Questions about your medicine?

A pharmacist can answer questions about your medicines for free, without an appointment. You can also ask your GP for a medication review. Check if you can get free prescriptions.