Medicines

Risedronate

Risedronate strengthens bones. It lowers the risk of fractures in osteoporosis.

Type of medicine
Bisphosphonate (bone-strengthening medicine)
Also known as
Actonel
Comes as
tablets
How you get it
Prescription only

What it is used for

  • Treating and preventing osteoporosis after the menopause
  • Osteoporosis in men
  • Preventing bone loss in people taking long-term steroids
  • Paget's disease of bone

Read our guides:

Off-label uses

Doctors sometimes prescribe a medicine for a condition it is not officially licensed for. This is called off-label use. It is legal and common when there is good evidence it helps, and your doctor should explain why they are suggesting it.

Risedronate is not commonly used off-label.

How it works

Risedronate slows down the cells that break down old bone. This lets bone-building cells catch up, so bones become denser and stronger.

Side effects

Like all medicines, Risedronate can cause side effects, although not everyone gets them. Many are mild and ease after the first few weeks.

Common side effects

  • indigestion
  • stomach pain
  • constipation or diarrhoea
  • headache
  • muscle and joint pain

Tell your doctor or pharmacist if these bother you or do not go away.

Serious side effects

These are rare. Call 111 or contact your doctor straight away if you get:

  • pain or difficulty swallowing, chest pain or new heartburn
  • jaw pain, a loose tooth or a mouth sore that does not heal
  • new pain in your thigh, hip or groin
  • ear pain or discharge

Call 999 if you have signs of a serious allergic reaction, such as swelling of your lips, mouth, throat or tongue, or trouble breathing.

You can report any side effect to the Yellow Card scheme, run by the medicines regulator.

Stopping and withdrawal

Important safety information

  • Take it first thing in the morning with a full glass of plain water, at least 30 minutes before food, drink or other medicines.
  • Stay upright for 30 minutes after taking it.
  • Have regular dental check-ups and tell your dentist you take it.
  • Make sure you get enough calcium and vitamin D.

Questions about your medicine?

A pharmacist can answer questions about your medicines for free, without an appointment. You can also ask your GP for a medication review. Check if you can get free prescriptions.

Official information

Last checked 5 October 2026. Tell us if something looks wrong.

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