What it is used for

Rheumatoid arthritis
Lupus (systemic and discoid)
Skin conditions made worse by sunlight

Read our guides:

Rheumatoid arthritis

Off-label uses

Doctors sometimes prescribe a medicine for a condition it is not officially licensed for. This is called off-label use. It is legal and common when there is good evidence it helps, and your doctor should explain why they are suggesting it.

Sjogren's syndrome
Some other inflammatory skin and joint conditions

How it works

Hydroxychloroquine changes how some immune cells work, which reduces inflammation and the immune system's attack on the body. It takes 2 to 3 months to work fully.

Side effects

Like all medicines, Hydroxychloroquine can cause side effects, although not everyone gets them. Many are mild and ease after the first few weeks.

Common side effects

feeling sick
stomach pain
diarrhoea
headache
skin rash
changes in skin colour

Tell your doctor or pharmacist if these bother you or do not go away.

Serious side effects

These are rare. Call 111 or contact your doctor straight away if you get:

changes in your eyesight, such as blurring or difficulty reading. Stop and contact your doctor
signs of low blood sugar, such as shaking, sweating and confusion
muscle weakness
a severe skin rash with blisters

Call 999 if you have signs of a serious allergic reaction, such as swelling of your lips, mouth, throat or tongue, or trouble breathing.

You can report any side effect to the Yellow Card scheme, run by the medicines regulator.

Stopping and withdrawal

Important safety information

It can damage the retina at the back of the eye with long-term use. You need regular eye checks after 5 years, or sooner if you are at higher risk.
Keep it away from children. Even a small number of tablets can be dangerous.

Questions about your medicine?

A pharmacist can answer questions about your medicines for free, without an appointment. You can also ask your GP for a medication review. Check if you can get free prescriptions.