Bisphosphonates
These are the most common bone medicines. They slow down the loss of bone.
- Alendronic acid or risedronate tablets, usually taken once a week
- Zoledronic acid, given as a drip into a vein once a year
Tablets must be taken first thing in the morning on an empty stomach, with a full glass of plain water, while sitting or standing upright. Wait at least 30 minutes before eating, drinking anything else, or taking other medicines.
Tell your dentist you take a bisphosphonate. Rarely, they can cause problems with the jaw bone, so regular dental checks matter.
Other medicines
- Denosumab, an injection every 6 months. It should not be stopped without a plan, because bone loss can speed up quickly afterwards.
- Teriparatide or romosozumab, injections for people with very high risk, usually started by a specialist
- Hormone replacement therapy (HRT), which can protect bones in women around the menopause
Calcium and vitamin D
Your doctor may suggest calcium and vitamin D supplements, especially if you do not get enough from food and sunlight. Everyone in the UK is advised to consider a vitamin D supplement in autumn and winter.
Treating fractures
Broken bones are treated in the usual way, with casts, surgery or pain relief. After a break, you should be offered a check of your bone health, often through a fracture liaison service.
Common questions
How long will I take bone medicine for?
Bisphosphonate tablets are usually reviewed after about 5 years (or 3 years for yearly drips). Some people then take a break, while others carry on. Your doctor will decide with you.
Sources we used
- NHS, Osteoporosis
- Royal Osteoporosis Society, Drug treatments
- NICE clinical knowledge summary, Osteoporosis
We check this page at least once a year, and sooner when the rules change. Read how we check our facts, or tell us if something looks wrong.