What it is used for

Overactive bladder, urgency and urge incontinence in adults

Read our guides:

Urinary incontinence

Off-label uses

Doctors sometimes prescribe a medicine for a condition it is not officially licensed for. This is called off-label use. It is legal and common when there is good evidence it helps, and your doctor should explain why they are suggesting it.

Vibegron is not commonly used off-label.

How it works

Vibegron stimulates beta-3 receptors in the bladder muscle. This relaxes the bladder while it fills, so it can hold more urine and you feel the urge less often.

Side effects

Like all medicines, Vibegron can cause side effects, although not everyone gets them. Many are mild and ease after the first few weeks.

Common side effects

headache
urine infections
diarrhoea
feeling sick
a cold or blocked nose

Tell your doctor or pharmacist if these bother you or do not go away.

Serious side effects

These are rare. Call 111 or contact your doctor straight away if you get:

being unable to pee, especially if you have an enlarged prostate

Call 999 if you have signs of a serious allergic reaction, such as swelling of your lips, mouth, throat or tongue, or trouble breathing.

You can report any side effect to the Yellow Card scheme, run by the medicines regulator.

Stopping and withdrawal

Important safety information

It may be recommended where anticholinergic bladder medicines are not suitable, for example in older people. Your GP will check if it is available locally.

Questions about your medicine?

A pharmacist can answer questions about your medicines for free, without an appointment. You can also ask your GP for a medication review. Check if you can get free prescriptions.