What it is used for

Depression
Panic disorder and social anxiety disorder
Generalised anxiety disorder
Obsessive compulsive disorder (OCD)
Post-traumatic stress disorder (PTSD)

Read our guides:

Off-label uses

Doctors sometimes prescribe a medicine for a condition it is not officially licensed for. This is called off-label use. It is legal and common when there is good evidence it helps, and your doctor should explain why they are suggesting it.

Premature ejaculation
Hot flushes during the menopause

How it works

Paroxetine is a selective serotonin reuptake inhibitor (SSRI). It increases serotonin in the brain, which helps regulate mood and anxiety.

Side effects

Like all medicines, Paroxetine can cause side effects, although not everyone gets them. Many are mild and ease after the first few weeks.

Common side effects

feeling sick
sweating
feeling sleepy or having trouble sleeping
dry mouth
sexual problems
weight gain
yawning

Tell your doctor or pharmacist if these bother you or do not go away.

Serious side effects

These are rare. Call 111 or contact your doctor straight away if you get:

thoughts of harming yourself or ending your life
unusual bleeding or bruising
signs of serotonin syndrome, such as confusion, high temperature and muscle twitching

Call 999 if you have signs of a serious allergic reaction, such as swelling of your lips, mouth, throat or tongue, or trouble breathing.

You can report any side effect to the Yellow Card scheme, run by the medicines regulator.

Stopping and withdrawal

Important safety information

It is not usually recommended in pregnancy. Talk to your doctor before trying for a baby, but do not stop suddenly.
Tell your doctor straight away if you feel worse or have thoughts of suicide, especially if you are under 25.

Questions about your medicine?

A pharmacist can answer questions about your medicines for free, without an appointment. You can also ask your GP for a medication review. Check if you can get free prescriptions.