What it is used for

Stomach cramps and bowel spasms in IBS
Similar symptoms in other bowel conditions such as diverticular disease

Read our guides:

Irritable bowel syndrome (IBS)

Off-label uses

Doctors sometimes prescribe a medicine for a condition it is not officially licensed for. This is called off-label use. It is legal and common when there is good evidence it helps, and your doctor should explain why they are suggesting it.

Mebeverine is not commonly used off-label.

How it works

Mebeverine acts directly on the smooth muscle of the bowel wall, relaxing it. This reduces spasms that cause pain, without slowing normal bowel movements.

Side effects

Like all medicines, Mebeverine can cause side effects, although not everyone gets them. Many are mild and ease after the first few weeks.

Common side effects

side effects are rare. Some people get indigestion or heartburn

Tell your doctor or pharmacist if these bother you or do not go away.

Serious side effects

These are rare. Call 111 or contact your doctor straight away if you get:

a skin rash or swelling of the face, which can be an allergic reaction

Call 999 if you have signs of a serious allergic reaction, such as swelling of your lips, mouth, throat or tongue, or trouble breathing.

You can report any side effect to the Yellow Card scheme, run by the medicines regulator.

Stopping and withdrawal

Important safety information

See a GP if you have new bowel symptoms over the age of 40, blood in your poo, weight loss or a change that lasts more than a few weeks.

Questions about your medicine?

A pharmacist can answer questions about your medicines for free, without an appointment. You can also ask your GP for a medication review. Check if you can get free prescriptions.