Medicines

Glycopyrronium

Glycopyrronium is used as a long-acting inhaler for COPD. As a liquid, it reduces severe drooling.

Type of medicine
Antimuscarinic medicine
Also known as
Seebri, Ultibro (with indacaterol), Trimbow (triple inhaler), Sialanar
Comes as
inhaler, liquid, tablets, injection
How you get it
Prescription only

What it is used for

  • Chronic obstructive pulmonary disease (COPD), as a once-daily inhaler
  • Severe drooling in children and young people with nerve conditions (liquid)
  • Reducing saliva and secretions during surgery or end-of-life care (injection)

Read our guides:

Off-label uses

Doctors sometimes prescribe a medicine for a condition it is not officially licensed for. This is called off-label use. It is legal and common when there is good evidence it helps, and your doctor should explain why they are suggesting it.

  • Excess sweating (hyperhidrosis), under a specialist

How it works

Glycopyrronium blocks acetylcholine receptors. In the lungs, this relaxes the muscles around the airways so they stay open for 24 hours. Elsewhere, it reduces saliva and sweat.

Side effects

Like all medicines, Glycopyrronium can cause side effects, although not everyone gets them. Many are mild and ease after the first few weeks.

Common side effects

  • dry mouth
  • constipation
  • difficulty peeing
  • a stuffy nose
  • headache

Tell your doctor or pharmacist if these bother you or do not go away.

Serious side effects

These are rare. Call 111 or contact your doctor straight away if you get:

  • wheezing that gets worse straight after using the inhaler
  • eye pain with blurred vision or seeing halos, which can be signs of glaucoma
  • being unable to pee

Call 999 if you have signs of a serious allergic reaction, such as swelling of your lips, mouth, throat or tongue, or trouble breathing.

You can report any side effect to the Yellow Card scheme, run by the medicines regulator.

Stopping and withdrawal

Important safety information

  • It may not be suitable if you have closed-angle glaucoma or problems peeing.

Questions about your medicine?

A pharmacist can answer questions about your medicines for free, without an appointment. You can also ask your GP for a medication review. Check if you can get free prescriptions.

Official information

Last checked 5 October 2026. Tell us if something looks wrong.

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