Medicines

Dexamfetamine

Dexamfetamine is a stimulant used to treat ADHD and narcolepsy. It helps with concentration and impulsive behaviour.

Type of medicine
Stimulant (ADHD medicine)
Also known as
Amfexa, Dexedrine
Comes as
tablets, liquid
How you get it
Started by a specialist, then sometimes prescribed by a GP

What it is used for

  • Attention deficit hyperactivity disorder (ADHD) in children and adults
  • Narcolepsy

Read our guides:

Off-label uses

Doctors sometimes prescribe a medicine for a condition it is not officially licensed for. This is called off-label use. It is legal and common when there is good evidence it helps, and your doctor should explain why they are suggesting it.

Dexamfetamine is not commonly used off-label.

How it works

Dexamfetamine increases the release of dopamine and noradrenaline in the brain. These chemical messengers help with attention, focus and controlling impulses.

Side effects

Like all medicines, Dexamfetamine can cause side effects, although not everyone gets them. Many are mild and ease after the first few weeks.

Common side effects

  • loss of appetite and weight loss
  • trouble sleeping
  • headache
  • dry mouth
  • a fast heartbeat
  • feeling anxious or irritable
  • stomach ache

Tell your doctor or pharmacist if these bother you or do not go away.

Serious side effects

These are rare. Call 111 or contact your doctor straight away if you get:

  • chest pain, fainting or a very fast or irregular heartbeat
  • seeing or hearing things that are not there, or feeling paranoid
  • a sudden change in mood or thoughts of harming yourself

Call 999 if you have signs of a serious allergic reaction, such as swelling of your lips, mouth, throat or tongue, or trouble breathing.

You can report any side effect to the Yellow Card scheme, run by the medicines regulator.

Stopping and withdrawal

Important safety information

  • It is a controlled drug. Keep it safe and never share it.
  • Your blood pressure, heart rate, weight and height (in children) will be checked regularly.
  • It can be misused. Tell your doctor if you have a history of drug misuse.
  • It is illegal to drive with certain levels in your blood, unless you take it as prescribed and your driving is not impaired.

Questions about your medicine?

A pharmacist can answer questions about your medicines for free, without an appointment. You can also ask your GP for a medication review. Check if you can get free prescriptions.

Official information

Last checked 5 October 2026. Tell us if something looks wrong.

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