Medicines

Brinzolamide

Brinzolamide eye drops lower the pressure inside the eye. They are used for glaucoma, often alongside other eye drops.

Type of medicine
Carbonic anhydrase inhibitor eye drops
Also known as
Azopt, Simbrinza (with brimonidine), Azarga (with timolol)
Comes as
eye drops
How you get it
Prescription only

What it is used for

  • Open-angle glaucoma
  • High pressure in the eye (ocular hypertension)

Read our guides:

Off-label uses

Doctors sometimes prescribe a medicine for a condition it is not officially licensed for. This is called off-label use. It is legal and common when there is good evidence it helps, and your doctor should explain why they are suggesting it.

Brinzolamide is not commonly used off-label.

How it works

Brinzolamide blocks an enzyme called carbonic anhydrase in the eye. This reduces the amount of fluid the eye makes, which lowers the pressure inside it.

Side effects

Like all medicines, Brinzolamide can cause side effects, although not everyone gets them. Many are mild and ease after the first few weeks.

Common side effects

  • blurred vision for a short time after using the drops
  • a bitter or unusual taste
  • eye irritation or discomfort

Tell your doctor or pharmacist if these bother you or do not go away.

Serious side effects

These are rare. Call 111 or contact your doctor straight away if you get:

  • eye pain, severe redness or a change in vision
  • a skin rash or swelling of the face

Call 999 if you have signs of a serious allergic reaction, such as swelling of your lips, mouth, throat or tongue, or trouble breathing.

You can report any side effect to the Yellow Card scheme, run by the medicines regulator.

Stopping and withdrawal

Important safety information

  • Shake the bottle well before use.
  • Leave at least 5 minutes between different eye drops.
  • Tell your doctor if you are allergic to sulfonamide (sulfa) medicines.

Questions about your medicine?

A pharmacist can answer questions about your medicines for free, without an appointment. You can also ask your GP for a medication review. Check if you can get free prescriptions.

Official information

Last checked 5 October 2026. Tell us if something looks wrong.

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